目的：B型钠尿肽（ proBNPⅡ）联合血清降钙素原（ PCT）在心功能不全及疑似合并肺部细菌感染患者诊断中的价值。方法：慢性心功能不全、肺部细菌感染、慢性心功能不全合并肺部细菌感染者各30例，同时测定PCT及proBNPⅡ。结果：30例肺部细菌感染患者PCT阳性29例，阳性率96.67%，同时测定proBNPⅡ，阳性3例，阳性率10.00%；30例慢性心功能不全急性发作患者PCT阳性2例，阳性率6.67%，同时测定proBNPⅡ，患者proBNPⅡ阳性30例，阳性率100.00%；30例慢性心功能不全合并肺部细菌感染者，PCT及proBNPⅡ阳性率均达100.00%。结论：PCT及proBNPⅡ联合检测可作为早期快速鉴别慢性心功能不全急性发作是否伴有肺部细菌感染的实验室指标，指导临床治疗方案及抗生素的合理应用。%Objective To explore the diagnostic value of B-type natriuretic peptide( BNP)combined with procalcitonin( PCT)in car-diac insufficiency patients with suspected pulmonary infections. Method Patients with chronic cardiac insufficiency(n=30),patients with pulmonary bacterial infection( n=30 ),and patients with chronic heart failure complicated with pulmonary bacterial infection( n=30 ) were enrolled in the study,all monitored PCT and proBNP II simultaneously. Results In patients with pulmonary bacterial infection,the pos-itive rate of PCT was 96. 67%(29 case),of proBNPⅡ was 10%(3 cases). In patients with chronic cardiac insufficiency,the positive rate of PCT was 6. 67%(2 case),of proBNPⅡwas 100%(30 cases). In patients with chronic heart failure complicated with pulmonary bacteri-al infection,the positive rate of PCT was 100%(30 case),of proBNPⅡwas 100%(30 cases). Conclusion Combined PCT and proBNPⅡmay contribute to identify whether chronic heart failure complicated with pulmonary bacterial infection or not early and rapidly,which may be helpful for reasonable decision of clinical treatment and application of antibiotics.
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