Objective Understanding of adult serum uric acid level and prevalence of hyperuricemia and the situation of ratio in need of medical treatment of Guangzhou area. Methods Determination of uric acid by enzymatic in January to November period in 2008 in our hospital for a medical examination of the serum uric acid level of the crowd. And statistical analysis using SPSS12.0 statistical software packages.Results Serum uric acid levels: male (403.39 ± 85.16) μ mol/L, female (305.84 ± 74.22) μ mol/L, the level of male BUA did not change significantly with age (P>0.05), female age gradually on the rise, the BUA male age group higher than that of female, there was a significant difference (P<0.001).Hyperuricemia prevalence rate: 35.15 percent for male, female 20.55 percent, 50-year-old former female hyperuricemia prevalence rate lower than that of male; after the 50-year-old age, the prevalence of hyperuricemia, close to or Higher than that of male. BUA level > 535 μ mol/L ratio: 6.29 percent for male, female 1.31 percent. The ratio of low hyperuricemia is: Male 1.06 percent, 0.69 percent female.Conclusion It's higher of serum uric acid level and prevalence of hyperuricemia and the proportion of need of drug treatment of hyperuricemia in patients in Guangzhou area, particularly in male. That should pay great attention to it and should provide early intervention and drug therapy. At the same time, We should pay attention to low hyperuricemia, and identify the causes and prevention of its complications.%目的 了解广州地区成人血尿酸水平与高尿酸血症患病率及需进行药物治疗的比例情况.方法 用尿酸酶法测定2008年1-11月期间来我院体检的人群血尿酸水平,并采用SPSS12.0统计软件包进行统计分析.结果 血尿酸水平:男性(403.39±85.16)μ mol/L,女性(305.84±74.22)μ mol/L,男性血UA(尿酸)水平随年龄增长变化不明显(P>0.05),女性有随年龄增长逐渐上升的趋势,各年龄组男性血UA水平均高于女性,有显著性差异(P<0.001).高尿酸血症患病率:男35.15%,女20.55%,50岁前女性高尿酸血症患病率低于男性;50岁后随年龄增长,高尿酸血症患病率接近或高于男性.血UA水平>535 μ mol/L比例:男6.29%,女1.31%.低尿酸血症比例为:男1.06%,女0.69%.结论 广州地区血尿酸水平和高尿酸血症患病率及需药物治疗的高尿酸血症患者比例较高,特别是男性,应对其提供早期干预及药物治疗;同时对低尿酸血症应引起重视,应查明病因,预防其合并症.
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