2型糖尿病并发脑梗死相关预测因素的分析

摘要

Objective To explore the relevant predicting factors for type 2 diabetes mellitus with cerebral infarction. Methods We enrolled 56 type 2 diabetic patients with cerebral infarction (DM+CI group) and 56 type 2 diabetic patients without cerebral infarction (DM group), and then analyzed their clinical data including sex, age, endogenous creatinine clearance rate (Ccr), urinealbumin excretion rate (UAER), fasting blood glucose (FBG) and HbAle. Results There were no significant differences between DM+CI group and DM group in sex, age, Ccr and FBG (P>0.05). However, UAER and HbAlc were obviously higher in DM+CI group than in DM group(P<0.05). UAER and HbAIc were closely related to DM with CI. Conclusion UAER and HbAle are the risk factors for DM with CI and can be. Used as the predictors for the disorder.%目的 探讨2型糖尿病合并脑梗死的相关预测因素.方法 分别收集2型糖尿病无并发脑梗死组(DM组)和2型糖尿病并发脑梗死组(DM+CI组)患者各56例,并对两组患者的性别、年龄、内生肌酐清除率、尿微量白蛋白排泄率、空腹血糖和糖化血红蛋白进行对照分析和Logistic回归分析.结果 两组比较,年龄、性别、内生肌酐清除率和空腹血糖差异无显著性(P＞0.05),而DM+CI组尿微量白蛋白排泄率和糖化血红蛋白分别为(27.89±6.42)mg/L、(7.98±0.69)%,较DM组升高且差异有显著性(P＜0.05): Logistic回归分析结果显示尿微量白蛋白排泄率(OR:1.627,P＜0.05)和糖化血红蛋白(OR:29.213,P＜0.05)为2型糖尿病合并脑梗死的独立危险因素.结论 尿微量白蛋白排泄率和糖化血红蛋白是2型糖尿病合并脑梗死的危险因素,两者可作为2型糖尿病合并脑梗死的相关预测因素.