首页> 中文期刊> 《国际医药卫生导报》 >低分子肝素钠联合阿司匹林治疗急性脑梗死的临床研究

低分子肝素钠联合阿司匹林治疗急性脑梗死的临床研究

摘要

Objective To investigate the efficacy and safety of using low molecular weight heparin in combination with aspirin to treat ACI in the first 6 hours at its onset. Methods 83 cases were divided into two groups: the treatment group (n=43) and the control group (n=40). The patients in the treatment group received 5000 units of subcutaneous injection of low molecular weight heparin twice a day and took 100mg aspirin once a day for a week. T he patients in the control group received subcutaneous injection of Placebo twice a day and took 100mg aspirin once a day for a week. Results Therapeutic outcome of the treatment group was obviously better than that of the control group with the cure rate 73.3% v 23.3%, which was really meaningful (P<0.01) .Conclusion The treatment in the first group got a quicker, stronger and better effect and was reliably safe.%目的 探讨低分子肝素钠联合阿司匹林治疗发病6小时内的急性脑梗死的效果及安全性.方法 选择83例急性脑梗死患者分为治疗组(43例)及对照组(40例),治疗组用低分子肝素钠5000单位皮下注射,1日2次,共7天,阿司匹林100毫克,1日1次,共7天.对照组用安慰剂皮下注射,1日2次,连续7天,阿司匹林100毫克,1日1次,共7天.结果 治疗组疗效明显优于对照组,治疗组痊愈率73.3%,对照组痊愈率23.3%,比较差异有极显著性(P<0.01).结论 低分子肝素钠联合阿司匹林治疗急性性脑梗死起效快、作用强、效果好、安全性可靠.

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