TREATMENT OF THROMBOSIS BY THE COMBINED APPLICATION OF THE INHIBITOR OF THE FACTOR Xa AND ASPIRIN, THE ACTIVATOR OF A TISSUE PLASMINOGEN (TPA), ANTAGONIST GPIIB / IIIA, A LOW-MOLECULAR HEPARIN OR HEPARIN

摘要

A method of treating thrombosis in a mammal is described by administering therapeutically effective amounts of a combination of (i) a factor Xa inhibitor and (ii) a compound selected from the group consisting of aspirin, TPA, a GPIIb / IIIa antagonist, low molecular weight heparin and heparin, in which the dose administered is at least one of (i) and (ii) is a subtherapeutic dose. Preferably, the combination of (i) and (ii) provides a synergistic effect. The international application was published together with an international search report.