应用呼吸机干预体系预防呼吸机相关性肺炎的临床研究

摘要

目的 以减少VAP的发生为最终目的,研究呼吸机干预体系预防VAP的有效性.方法 我院重症监护室(ICU)2009年1月-2010年6月收治的行机械辅助通气治疗的患者,随机分为呼吸机干预体系组(实验组)和常规医疗护理组(对照组),以VAP感染率、机械通气时间、ICU住院时间、病死率及抗生素费用为观察指标,评价呼吸机干预体系的实施效果.结果 实施呼吸机干预体系可明显降低VAP的感染率(4.21‰ vs 17.49‰,P=-0.039)且缩短住院时间(12.49日vs 17.20日,P=O.005)和持续通气时间(8.65日vs 10.66日,P=0.027),两组比较差异均有显著性.结论 呼吸机干预体系是顶防VAP的发生、节约医疗资源、保证病人安全的最佳策略.%Objective To reduce the incidence of VAP and evaluate the effectiveness of 'Ventilator Bundle'. Methods Selected these ICU patients, who received mechanical ventilation and were admitted from Jan. 2009 to Jun. 2010, and randomly divided them into ventilator bundle group (Experimental Group) and routine medical care group (Control Group). The research would use VAP infection rate,ventilation time, ICU stay, morbidity and mortality and antibiotic cost to evaluate the effectiveness of Ventilator Bundle. Results The Ventilator Bundle can obviously reduce VAP infection rate (4.21% vs 17.49‰, P=0.039), ICU stay (12.49 days vs 17.20 days, P=0.005) and ventilation time (8.65 days vs 10.66 days, P=0.027). Conclusion Ventilator Bundle is the best strategy to prevent the incidence of VAP,save medical resources and protect the safety of patient.