药物不良反应与治疗成本费用分析

摘要

Objective To investigate the characteristics of adverse drug reactions (ADR) in our hospital and its influence on the hospitalization expenses, and to promote the reasonable drug using in clinical medicine. Method 120 ADR cases had been collected from January 2007 to March 2009. And analyzed the drug species and clinical situation of a1l the cases, and analyzed the ages of all patients. Then used pharmacoeconomics to analyze the ADR treatment cost of 83 cases. Results Among 120 ADR cases, the highest proportion is the elderly people, which accounted for 45.83%. ADR was mainly caused by antibiotics, central nervous system drugs and traditional Chinese medicine preparation. The total ADR treatment cost of 83 patients was 6666.51 yuan; the highest single case was 1753.32 yuan; and it was 80.32 yuan per patient. Conclusion Monitoring of adverse drug reactions and prevent the occurrence of adverse drug reactions are effective ways to promote reasonable drug using in clinical medicine.%目的 分析我院药物不良反应(ADR)发生的特点及其对住院治疗费用的影响,促进临床合理用药.方法 对2007年-2009年3月收集得的120例ADR报告分别从药物种类、临床表现及患者年龄等方面进行统计分析.并运用药物经济学分析其中83例ADR的治疗成本.结果 在120例ADR中,老年人占的比例最高,占45.83%;引起ADR的药物主要为抗生素、中枢神经系统药物及中药制剂;其中83例ADR的治疗总成本为6666.51元,单例最高达1753.32元,平均每例为80.32元.结论 监测药物不良反应,预防药物不良反应的发生,是促进临床合理用药的有效手段.