保留膀胱手术加髂内动脉化疗治疗浸润性膀胱癌的临床观察

摘要

目的 探究分析对于浸润性膀胱癌患者采取保留膀胱手术联合髂内动脉化疗的临床治疗效果.方法 采用回顾性分析的方法,分析了我院2005年1月至2007年1月收治的116例浸润性膀胱癌患者的临床资料,根据治疗方法的不同,将本组患者随机分成对照组和实验组各58例,对照组患者给予保留膀胱手术治疗,实验组患者给予保留膀胱手术联合髂内动脉化疗.分析比较两组患者的临床治疗有效率和生存情况.结果 实验组患者的临床治疗有效率明显高于对照组,差异有统计学意义(89.66％ vs.72.41％;x2=4.54,P＜0.05);实验组患者的1年生存率、3年生存率和5年生存率明显高于对照组,差异有统计学意义(P＜0.05).结论 对于浸润性膀胱癌患者,给予其保留膀胱手术联合髂内动脉化疗的临床治疗效果较好,能够显著提高近期临床治疗有效率,同时提高1年、3年和5年的远期生存率,值得临床推广使用.%Objective To investigate the clinical efficacy of bladder-preserving surgery combined with internal iliac artery chemotherapy in the treatment of invasive bladder cancer.Methods Clinical data of 116 cases of invasive bladder cancer in our hospital from January 2005 to January 2007 was retrospectively analyzed.All patients were randomly divided into control group and experimental group according to treatment methods,58 cases in each group.Control group was treated with bladder-preserving surgery,while experimental group was treated with bladder-preserving surgery combined with internal iliac artery chemotherapy.Compared the clinical efficacy and survival situation of two groups.Results The treatment efficiency of experimental group was significantly higher than that of control group (89.66％ vs.72.41％;x 2=4.54,P＜0.05);1-year,3-year and 5-year survival rate of experimental group were significantly higher than those of control group (P＜0.05).Conclusions Bladder-preserving surgery combined with internal iliac artery chemotherapy in the treatment of invasive bladder cancer has good clinical efficacy,which can significantly improve short-term clinical treatment efficiency,1-year,3-year and 5-year survival rate,worthy of clinical application.