Objective To study the effect of FPG,2hPG,and HbA1c in the diagnosis of patients with diabetes and to provide clinical evidence for the diagnosis of diabetes.Methods 120 patients diagnosed with diabetes at our hospital from March,2014 to March,2015 were chosen as a diabetes group and 100 healthy objects taking physical examination at our hospital as a control group.Both groups were fasting 8 h.Fasting blood was collected for detecting FPG and HbAlc.2hPG was detected in each group 2 h after collecting fasting blood.The FPG,2hPG and HbA1c levels of the two groups were observed and recorded.The diagnostic rates and the sensitivities of different diagnostic criteria were recorded.Results The levels of FPG,2hPG,and HbAlc were significantly higher in the diabetic group than in the control group.Using FPG ≥ 7 mmol/L as diagnostic criteria,the diagnosis rate was 47.5％;using 2hPG ≥11.1 mmol/L as diagnostic criteria,the diagnosis rate was 91.7％;using HbA1c ≥6.5％ as diagnostic criteria,the diagnosis rate was 90.0％;and using the three as diagnostic criteria,the diagnosis rate was 98.3％.The diagnostic rate and sensitivity of the combined detection of the three in the diagnosis of diabetes were significantly higher than those of any other diagnostic criteria (P ＜ 0.05).Conclusions The combined detection of FPG,2hPG,and HbA1c can increase diabetes diagnosis rate and sensitivity and decrease missed diabetes diagnosis rate,so it has important clinical significance and value in diabetes screening,diagnosis,and risk assessment.%目的 研究FPG、2hPG、HbA1c对糖尿病患者的诊断效果,为诊断糖尿病病人提供临床依据.方法 选择2014年3月至2015年3月于本院诊断为糖尿病的病人120例作为糖尿病组,对照组为本院100例健康体检者,各组对象均空腹8h后,采集空腹血液检测FPG和HbA1c指标.各组对象在抽取空腹血液2h后进行2hPG检测.观察并记录两组FPG、2hPG、HbA1c水平,记录不同诊断标准下的确诊率、灵敏度等指标.结果 与对照组相比,糖尿病组FPG、2hPG及HbA1c水平均明显较高;诊断标准采用FPG≥7.0 mmol/L时,糖尿病组确诊率为47.5％;诊断标准采用2hPG≥11.1 mmol/L时,确诊率为91.7％;诊断标准采用HbA1c≥6.5％时,确诊率为90.0％;采用三项指标联合进行诊断时,确诊率为98.3％.三者联合检测诊断糖尿病的确诊率和灵敏度均明显高于其他任一诊断标准(P＜0.05).结论 FPG、2hPG、HbA1c联合检测能使糖尿病的确诊率得到进一步提高,漏诊率进一步减少,使糖尿病诊断的灵敏度提高,在糖尿病的筛查、诊断和风险评估上具有重要的临床意义和价值.
展开▼
