目的评价超声介导下细针穿刺活检（USFNA）在腮腺肿瘤术前诊断中的价值。方法检索中国生物医学文献库、 Medline、 Embase，收集相关文献，使用诊断性试验质量评价标准对文献质量进行评价。使用MetaDisc 1.4进行Meta分析。结果10篇文献符合纳入标准。 Meta分析结果显示， USFNA分辨腮腺肿瘤良恶性的合并诊断指标及其95%可信区间（95%CI）如下：特异度0.99，95%CI（0.98，1.00）；敏感度0.86，95%CI（0.78，0.91）；阳性似然比42.39，95%CI（22.03，81.57）；阴性似然比0.20，95%CI（0.13，0.29）；受试者工作曲线下面积0.9830。结论 USFNA在腮腺肿瘤的良恶性鉴别中具有较高的特异度和敏感度，可作为常规术前检查之一。% Objective To evaluate the diagnostic value of ultrasound-guided fine-needle aspiration(USFNA) in differentiating malignancy and benign lesions of the parotid gland. Methods The diagnostic studies on ultrasonog-raphy guided fine-needle aspiration cytology for parotid tumors were searched through Chinese biomedical literature database, Medline and Embase. The methodological quality was assessed with quality assessment of diagnostic ac-curacy studies. Two reviewers took part in all of the work in duplicate and any disagreement was resolved by discussion. Meta-analysis was done with MetaDisc 1.4. Results A total of 10 studies were included. The results of meta-analysis showed the pooled diagnostic values and its 95% confidence interval(95%CI) in differentiating malignant and benign tumors in the parotid gland as following: Specificity 0.99, 95%CI(0.98, 1.00); sensitivity 0.86, 95%CI(0.78, 0.91); positive likelihood ratio 42.39, 95%CI(22.03, 81.57); negative likelihood ratio 0.20, 95%CI (0.13, 0.29); the area beneath the receiver operating characteristic curve was 0.983 0. Conclusion The ultrasono-graphy guided fine-needle aspiration cytology showed a high specificity and sensitivity in differencing the malignant and benign tumor of the parotid region, which should be used as a routine test before operation.
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