fMRI在癫大脑网络中的研究进展

摘要

Epilepsy is a chronic paroxysmal neurological disorder that caused by abnormal discharge of neurons. Because of its repetitive seizures, complex and various clinical manifestation, the structure and function of the brain both have been severely damaged. In recent years, with the rapid development of functional imaging technology, functional magnetic resonance imaging (fMRI) has been widely used in the evaluation of epilepsy. Particularly the resting-state fMRI alone or combining with EEG plays an important role in revealing the characteristics of the changes in complex network, structure network and functional network. It helps us to understand deeply about the pathogenesis of epilepsy.%癫日是神经元异常放电所致的慢性发作性神经功能障碍性疾病，因其发作的反复性、复杂性和多样性，大脑的结构和功能均受到严重损害。近年来，随着功能成像技术的不断发展，功能MR成像（fMRI）在癫日中的应用越来越广泛，尤其是静息态 fMRI（rs-fMRI）和同步联合脑电图 fMRI（EEG-fMRI）的应用揭示了癫日复杂网络、结构网络及功能网络改变的特点，为理解癫日发病机制提供了重要的帮助。