Objective To inquire into the relationship between high sensitivity C-reactive protein(hs-CRP) and T-lymphocyte subpopulation in the seriously injured and its significance. Methods The 83 seriously injured(ISS≥16) were divided into 2 groups according to the infection in the course of treatment, or the infection group and the non-infection group. The levels of hs-CRP and T-lymphocyte subpopulation were detected 1,2,3 and 7 days after trauma. Twenty healthy persons were used as controls for comparison at the same time. Results In the non-infection group,the level of hs-CRP rose at first and fell later,the levels of total T cells (CD3+),T, cells(CD3+CD4+) and T4/T8 (CD3+ CD4 + /CD3+ CD8+ ) fell at first and rose later and the level of T8 cells(CD3 + CD8+) rose at first and fell later while in the infection group,the level of hs-CRP rose continuously and the levels of total T cells and Tt /T8 fell continuously. Hs-CRP and T-lymphocyte subpopulation change showed a significant difference each day after trauma in both groups compared with the control groupCP展开▼
