西北4省区蜱虫自然感染3种病原体的分子流行病学研究

摘要

Objective To investigate the existence of Borrelia burgdorferii,Francisella tularensis and Coxiella burnetii in ticks in Northerwestern China. Methods Tick samples were collected and detected by molecular methods. Results A total of 2 460 ticks of 11 species were collected and tested for evidence of Borrelia burgdorferii,Francisella tularensis and Coxiella burnetii. There 304,75 and 200 ticks harboring DNA of Borrelia burgdorferi,Francisella tularensis and Coxiella burnetii,respectively. Conclusion The infections of Borrelia burgdorferii,Francisella tularensis and Coxiella burnetii in ticks were proved to exist in Northerwastern China exists.%目的 了解西北4省区蜱虫自然感染莱姆病螺旋体、土拉弗氏菌和Q热立克次体的情况.方法 采用布旗法收集西北地区内的蜱标本进行分子生物学检测.结果 文献调研显示:西北地区已报道的虫媒疾病共有15种.西北地区内共采集蜱标本2 460只,涉及11个不同蜱种.共有304只蜱标本检测发现莱姆病螺旋体,75只感染土拉弗菌,200只感染Q热立克次体,3种病原体在4个调查点内均存在.共采集到西北地区内当地人群血清725份,共有183份血清存在目标抗体,进一步证实调查疾病的存在.结论 证实西北四省区存在3种蜱媒疾病在,对预防控制具有重要意义.