老年股骨粗隆骨折患者γ-谷氨酰转肽酶、碱性磷酸酶、超敏C反应蛋白联合检测的临床意义

摘要

目的 探讨老年股骨粗隆骨折患者γ-谷氨酰转移酶(GGT)、碱性磷酸酶(ALP)、超敏C反应蛋白(hs-CRP)联合检测的临床意义.方法 回顾性分析67例老年股骨粗隆骨折患者的GGT、ALP、hs-CRP水平,并研究术后不同时间点各指标相对于术前的变化情况及不同降低水平的预后情况.结果 老年股骨粗隆骨折患者的GGT、ALP及hs-CRP水平高于健康对照者和其他部位骨折患者,且与病理参数有关;术后呈降低的趋势;老年股骨粗隆骨折患者中三项指标术后水平降幅较大者的Harris髋关节功能评分累积优良率高于降幅者低者,差异有统计学意义(P<0.01).结论 监测老年股骨粗隆骨折患者的血清GGT、ALP及hs-CRP水平及其术后的变化情况具有重要的临床意义.%Objective To explore the clinical significance of y glutamyl transferase(GGT) ,alkaline phosphatase(ALP) and high sensitivity C reactive protein(hs CRP) detection in elderly patients with subtrochanteric fractures. Methods GGT, ALP and hs CRP levels in 67 elderly patients with subtrochanteric fractures were retrospectively analyzed,and the changes of them before oper ation and at different postoperative time points as well as the prognosis of reducing level were also analyzed. Results GGT,ALP and hs CRP levels in patients with subtrochanteric fractures were higher than in health people and patients with other fractures,and were related to the pathological parameters. The three indicators showed a decreasing trend after operation. The Harris hip score ac cumulated good rates in high level decreasing groups were higher than those in low level decreasing groups(P<0. 01). Conclusion GGT,ALP and hs CRP levels and changes before and after surgery in elderly patients with subtrochanteric fractures might be with important clinical significance.