宁明县艾滋病哨点人群HIV、HCV、TP检测结果分析

摘要

目的 了解宁明县艾滋病(AIDS)哨点人群的人类免疫缺陷病毒(HIV)、丙型肝炎病毒(HCV)和梅毒螺旋体(TP)的感染情况,为制定相应疾病干预措施提供科学依据.方法 按照<全国艾滋病哨点监测实施方案>要求,对暗娼、吸毒者、孕产妇人群采集血样,用酶联免疫吸附试验(ELISA)检测 HIV、HCV、TP 抗体,并对其结果进行统计学处理.结果 2009～2012年哨点人群HIV、HCV和TP抗体分别检测4 599例、4 583例和4 525例,检出阳性分别为242例、1 073例和333例,阳性率分别为5.26%、23.41%和7.36%.暗娼、吸毒者、孕产妇HIV检出率分别为2.36%、14.06%和0.56%,差异有统计学意义(P＜0.01),HCV检出率分别为4.23%、72.73%和0.31%,差异有统计学意义(P＜0.01),TP检出率分别为8.8%、13.19%和0.94%,差异有统计学意义(P＜0.01).结论 宁明县HIV、HCV、TP感染率最高的人群是吸毒人群,今后在防控中要加大力度对吸毒人群的监管.梅毒呈逐年上升趋势,迫切需要有针对性的行为干预和治疗,防止疫情的蔓延.%Objective To investigate the infection rates of HIV, HCV and syphilis among AIDS sentinel surveillance population in Ningming and provide scientific evidence for the development of appropriate prevention and control measures.Methods According to the National AIDS Sentinel Surveillance Implementation Plan, female sex workers, drug users and pregnant women blood samples were collected and KLISA was used to detect antibodies of HIV, HCV and TP.The detection results were statistically analyzed.Results During 2009-2012,4 599,4 583 and 4 525 cases were detected for antibodies of HIV,HCV and TP,and 242,1 073 and 333 cases were positive respectively with HIV,HCV and TP with positive rates of 5.26%,23.41% and 7.36% respectively.The HIV detection rates of female sex workers,drug users and pregnant women were 2.36%,14.06% and 0.56% respectively, with statistical significant differences(P<0.001).The HCV detection rates of female sex workers,drug users and pregnant women were 4.23%,72.73% and 0.31% respectively,with statistical significant differences(P<0.001).The TP detection rates of female sex workers,drug users and pregnant women were 8.8%,13.19% and 0.94% respectively, with statistical significant differences (P<0.001).Conclusion In Ningming,the infection rates of HIV,HCV and TP might be much higher in the surveyed drug users, disease control and prevention should be strengthened.The incidences of syphilis might increase yearly,behavioral intervention and syphilis treatment should be strengthened to prevent the spread of epidemic situation.