Objective To analyse distribution of age and gender characteristics of specific IgG(sIgG)antibodies and specific IgE (sIgE)antibodies of 13 types of food allergens in patients with food anaphylaxis,and to explore the relationship between sIgG and sIgE in food anaphylaxis.Methods 314 cases of patients from 2009 to 2012 were selected as subjects,and divided into underage group(1 63 cases)and adult group(1 5 1 cases).Serum sIgG of 13 types of food allergens were detected by using enzyme linked immu-nosorbent assay,serum sIgE of these food allergens were detected by using immune capture.Results 80.25% of the patients were sIgG-positive,and no obvious gender differences were found;while the positive rates of sIgG in the underage group(94.48%)were higher than that in the adult group(64.90%),there were statistically significant differences(P < 0.05 ).34.39% of the patients were sIgE-positive.The positive rates of sIgE in male patients(40.68%)were higher than that in female patients(26.28%),and that in the underage group(55.21%)were also higher than that in the adults group(1 1.92%),there were statistically significant differences(P <0.05).Conclusion The total positive rates and its distribution characteristics of sIgG and sIgE of same food aller-gens were obviously different.Food anaphylaxis might be associated with age,gender,food types and individual diversity.%目的：分析食物过敏患者血清中13种相同食物变应原特异性 IgG(sIgG)和特异性 IgE(sIgE)在不同年龄和性别间的分布特征,探讨两者在食物过敏性疾病中的关系。方法以2009~2012年门诊314例患者为研究对象,并根据年龄分为未成年组(163例)与成年组(151例)；通过酶联免疫吸附试验检测患者血清中13种食物变应原 sIgG,同时通过免疫捕获法检测患者血清中的 sIgE。结果80.25%的患者 sIgG 呈阳性反应,阳性率无明显性别差异,但未成年组(94.48%)高于成年组(64.90%),差异有统计学意义(P <0.05)；34.39%的患者 sIgE 呈阳性反应,男性阳性率(40.68%)高于女性(26.28%),未成年组(55.21%)高于成年组(11.92%),差异均有统计学意义(P <0.05)。结论相同食物变应原的 sIgG 和 sIgE 总阳性率差异较大,两者的阳性分布特征也有不同,食物过敏性疾病与年龄、性别、食物种类和个体特异性相关。
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