目的 探讨红细胞分布宽度(RDW)、中性粒细胞/淋巴细胞比值(NLR)在妊娠期糖尿病(GDM)患者中的变化.方法 将2016年1月至2016年10月于广州市妇女儿童医疗中心产科就诊的160例孕妇纳入该研究.将诊断为妊娠糖尿病(GDM)的80例患者作为GDM组,正常妊娠孕妇80例作为对照组,分析孕中期(24~28周)孕妇的临床资料、RDW及NLR的变化.结果 GDM组孕妇与对照组孕妇在年龄、孕周、既往孕产次及孕前体质量指数(BM I)方面比较,差异均无统计学意义(P>0.05).GDM组孕妇高血压家族史及巨大儿的发生率与对照组比较差异无统计学意义(P>0.05),而GDM组孕妇糖尿病家族史、胎膜早破及早产的发生率与对照组相比,差异有统计学意义(P<0.05).GDM组RDW、NLR水平均高于对照组(P<0.01).结论 GDM与炎症之间有一定的联系.%Objective To explore the change of red cell volume distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) in the patients with gestational diabetes mellitus (GDM ) .Methods A total number of 160 pregnant women in our center from January to October 2016 were selected as the research subjects .Eighty patients with GDM served as the GDM group and 80 normal pregnant women as the control group .The clinical data at the second trimester (24 to 28 gestational weeks) ,and changes of RDW and NLR were analyzed .Results The age ,gestational weeks ,gestational times and pre-pregnant BMI had no statistical differences between the GDM group and control group (P>0 .05) .There was no statistically significant differences in the hyperten-sion family history and fetal macrosomia incidence between the GDM group and control group .However ,the family history of diabe-tes ,premature rupture of membranes and incidence of premature birth had statistical difference between the two groups (P<0 .05) . The RDW and NLR levels of the GDM group were higher than those of the control group (P<0 .01) .Conclusion GDM has a cer-tain association with inflammation .
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