Dialog vario嵌体修复牙邻面牙体缺损的临床疗效及对龈沟液炎性因子与氧化应激分子水平的影响

摘要

目的 探讨Dialog vario嵌体修复牙邻面牙体缺损的临床疗效及其对龈沟液炎性因子与氧化应激分子水平的影响.方法 选择该院2012年9月至2015年9月收治的104例牙邻面牙体缺损患者,按治疗方式分为研究组和对照组,每组52例,对照组采用e-max嵌体修复,研究组采用Dialog vario嵌体修复.比较2组临床疗效,龈沟液中白细胞介素(IL)-1β、IL-6、IL-8、肿瘤坏死因子-α(TNF-α)、丙二醇(MDA)、超氧化物歧化醇(SOD)、谷胱甘肽过氧化物酶(GSG-Px)水平,以及牙龈情况.结果 研究组修复体完整性、边缘密合度、颜色匹配及继发龋均优于对照组(P＞0.05).研究组IL-β、IL-6、IL-8、TNF-α、MDA低于对照组(P＜0.05),SOD、GSH-Px高于对照组(P＜0.05).研究组牙龈状态优于对照组(P＜0.05).结论 Dialog vario嵌体修复牙邻面牙体缺损的临床疗效确切,可能与其能够减轻龈沟液炎性反应与氧化应激有关.%Objective To research the clinical efficacy of Dialog vario inlay teeth adjacent surface tooth repair and the influence on inflammatory factor and oxidative stress molecules in gingival sulcus fluid.Methods From September 2012 to September 2015,104 patients with ortho dental defects treated in the hospital were divided into study group and control group,with 52 cases in each group,control group used e-Max inlay repair,the research group used Dialog vario inlay repair.Clinical curative effect,beta interleukins-1β,6,8 (IL-β,IL-6,IL-8),tumor necrosis factor-α (TNF-α),propylene glycol (MDA),superoxide disproportionation alcohol (SOD),glutathione peroxidase (GSH-Px),gum situation were compared between two groups.Results The replacement integrity,marginal consistency,color matching and secondary caries rate in the study group were superior to those of the control group (P＞ 0.05).IL-β,IL-6,IL-8,TNF-α,MDA of study group were lower than the control group (P＜0.05).SOD and GSH-Px of study group were higher than those of the control group(P＜0.05).Periodontal status of research group was better than that of control group (P＜0.05).Conclusion The clinical efficacy of Dialog vario inlay in the repair of ortho dental defects may be related to the reduction of inflammatory reaction in gingival crevicular fluid and oxidative stress.