反复针刺分离联合结膜下注射5-FU治疗青光眼术后滤过泡功能不良

摘要

目的:评估以反复针刺分离联合结膜下注射5-FU的方法处理青光眼术后功能不良滤过泡的效果.方法:回顾性分析2009-03/2013-02在我院以反复针刺分离联合结膜下注射5-FU的方法处理因青光眼术后滤过泡功能不良而眼压升高的连续病例34例34眼.分析治疗后眼压、滤过泡形态的变化及眼部并发症.结果:治疗后平均眼压从35.51mmHg降至14.43mmHg(P<0.05),成功率达91%.常见并发症包括角膜上皮损伤、结膜撕裂和脉络膜脱离等.结论:反复针刺分离联合结膜下注射5-FU的方法处理青光眼术后滤过泡功能不良安全有效.%AIM: To evaluate the therapeutic efficacy of a repeated bleb needling technique combined with subconjunctival injection of 5-FU in eyes with previous glaucoma surgery that had malfunctional filtering blebs.METHODS: A retrospective review of 34 consecutive patients (34 eyes) of repeated bleb needling combined with subconjunctival injection of 5-FU in eyes, which had malfunctional filtering blebs after previous glaucoma surgery in our hospital from March 2009 to February 2013 was performed. The intraocular pressures (IOP), shapes of filtering blebs and complications after surgery were analyzed.RESULTS: There was significant reduction of mean IOP from 35.51 mmHg to 14. 43mmHg (P<0. 05). The overall success rate was 91%. The general complications included damage of corneal epithelium, conjunctiva torn, and choroidal detachment.CONCLUSION: Repeated needling with adjunctive 5-FU proved a highly effective, safe alternative to treat malfunctional filtering blebs after previous glaucoma surgery.