不同类型葡萄膜炎患者致病原因分析

摘要

目的：分析不同类型葡萄膜炎患者的致病原因。　　方法：选取2012-06/2015-06在我院进行诊治的葡萄膜炎患者60例120眼，所有患者均由同一葡萄膜炎专科医生，按照统一诊疗规范进行检查。依据国际葡萄膜炎研究定制的标准，将其分为：前葡萄膜炎、中葡萄膜炎、后葡萄膜炎、全葡萄膜炎。观察患者的年龄、性别、葡萄膜炎类型及患病原因。　　结果：通过对患者的病因及临床类型分析，所选葡萄膜炎患者主要特发性26眼(21.7%)、VKH 综合征18眼(15.0%)、HLA-B27相关性14眼(11.7%)、病毒性12眼(10.0%)、Fuchs 综合征8眼(6.7%)、Behcet 病8眼(6.7%)、糖尿病6眼(5.0%)、梅毒6眼(5.0%)、青光眼睫状体综合症6眼(5.0%)、幼年型慢性关节炎4眼(3.3%)、交感性眼炎4眼(3.3%)、外伤性2眼(1.7%)、类肉瘤2眼(1.7%)、眼内炎2眼(1.7%)、其他2眼(1.7%)；通过对不同葡萄膜炎的病因观察，前葡萄膜炎病因主要有特发性病例，其次是HLA-B27相关性、病毒性；全葡萄膜炎的治病原因中以VKH综合征、特发性病例和Behcet病为主；后葡萄膜炎主要是特发性病例，其次是病毒性感染；中间葡萄膜炎以特发性病例为主。　　结论：通过对临床患者观察分析，葡萄膜炎患者男性多于女性；特发性、VKH 综合征、病毒性伴发的葡萄膜炎和Behcet病是其常见的葡萄膜炎类型。%AlM:To analysis and discuss etiology of different types of uveitis. METHODS:We selected 60 patients ( 120 eyes ) with uveitis treated in our hospital from June 2012 to June 2015. All patients examined by the same uveitis specialist with unified standards. According to international standards, uveitis was customized into:anterior uveitis ( AU) , intermediate uveitis ( lU) , posterior uveitis ( PU) , panuveitis ( PanU ) . Age, gender, type of uveitis and causes of the disease were analyzed. RESULTS:Through the analysis of the etiology and clinical types of patients, the main types were idiopathic (26 cases, 21. 7%), VKH syndrome (18 cases, 15. 0%), HLA-B27 related (14 cases, 11. 7%), viral (12 cases, 10. 0%), Fuchs syndrome ( 8 cases, 6. 7%), Behcet’s disease ( 8 eyes, 6. 7%), diabetes ( 6 eyes, 5. 0%), syphilis (6 eyes, 5. 0%), Posner-Schlossman syndrome (6 eyes, 5. 0%), juvenile chronic arthritis(4 eyes, 3. 3%), sympathetic ophthalmia ( 4 eyes, 3. 3%), traumatic ( 2 eyes, 1. 7%), sarcoid(2 eyes, 1. 7%), endophthalmitis (2 eyes, 1. 7%) and others ( 2 eyes, 1. 7%). By the observation for different types uveitis, the main cause of AU was idiopathic, followed by HLA-B27-related and viral;for PanU, it was VKH syndrome, idiopathic ones and Behcet’s disease;for PU, it was idiopathic, then viral;for lU, it was idiopathic. CONCLUSlON:Through observation and analysis for clinical patients, male patients were more than female;idiopathic, caused by VKH syndrome, viral and Behcet’s disease are the common types of uveitis.