• AIM: To explore the morphology and immune phenotypic characteristics of lymphoma from ocular adnexal mucosa-associated lymphoid tissue ( OAML) .•METHODS:The characteristics of morphology, cytology and immune phenotype of the lymphoma were observed by light microscope and immunohistochemistry.• RESULTS: Twenty -nine cases ( 33 eyes ) with lymphoma including 23 cases (24 eyes) in phaseⅠand 6 cases ( 9 eyes ) in phase Ⅱ.Small lymphocytes tumor cells were observed and took predominant place in all cases. The tumor cells, almost had the same size, diffused in the tissues, and the nuclei was almost round with dyed deep, while the cytoplasm was less with dyed pale.There were 29 cases with CD20 (+) and CD79a (+), 2 cases with CD5 (+) and 3 cases with CD43 (+);CD45RO, CyclinD1, CD10 and CD23 were found negative in all cases.•CONCLUSION: Infiltration of small lymphocytes-like tumor cells is main type that we found in the lymphoma from MALT, with a few center -cell -like cells and mononuclear cells scattered.Plasma cells and Russell, Dutcher bodies are seen in some cases. The typical immune phenotype of lymphoma from OAML is CD20 (+) , CD10 (-) , CD5 (-) , CD23 (-) and CyclinD1 (-) . Some cases have CD5 (+) expression, which may be a signal of bad outcomes of OAML.%目的：探讨眼附属器黏膜相关淋巴组织淋巴瘤（ mucosa－associated lymphoid tissue，MALT）形态及免疫表型特点。方法：采用光镜观察和免疫组织化学分析MALT的形态学、细胞学、免疫表型的特点。结果：眼附属器MALT患者29例33眼中，Ⅰ期23例24眼，Ⅱ期6例9眼。29例33眼均以小淋巴细胞样瘤细胞为主，瘤细胞弥漫分布，体积小，大小较均一，细胞核略呈圆形，染色深，细胞质少，染色淡；29例CD20及CD79 a均（＋），CD5（＋）2例， CD43（＋）3例；所有患者 CD45 RO、CyclinD1、CD10、CD23均为（－）。结论：眼附属器MALT主要以小淋巴细胞样瘤细胞浸润为主，散在分布中心细胞样细胞及单核样细胞，部分可见浆细胞及Russel、Dutcher小体。眼附属器MALT典型的免疫表型CD20（＋）、CD10（－）、CD5（－）、CD23（－）、CyclinD1（－），少数患者CD5（＋）， CD5（＋）可能是眼附属器MALT预后不好的一个信号。
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