三种不同造影方式在糖尿病性视网膜病变诊断中的应用对比

摘要

目的:比较分析虹膜荧光血管造影(iris fluorescein angiography,IFA)联合眼底荧光血管造影(fundus fluorescein angiography,FFA)、吲哚菁绿血管造影(indocyanine green angiogrsphy,ICGA)和FFA在早期糖尿病性视网膜病变(diabetic retinitis,DR)中的诊断价值.方法:选择2015-08/2016-08期间我院收治的DR患者70例136眼,全部患者分别接受ICGA、FFA、IFA+ FFA检查,分析三种造影方式的检出结果.结果:FFA检出病变120眼(88.2％),ICGA检出病变124眼(91.2％),IFA+FFA检出病变130眼(95.6％),三种检查方法病变检出率比较,差异无统计学意义(P＞0.05);FFA检出48眼出现新生血管,18眼玻璃体积血,38眼黄斑水肿,16眼无灌注区;ICGA检出49眼新生血管,38眼黄斑水肿,17眼玻璃体积血,20眼无灌注区;IFA+FFA检出17眼增殖性糖尿病性虹膜病变(DI),22眼非增殖性DI,5眼NVG,92眼无DI.结论:在DR诊断中,IFA+ FFA、FFA、ICGA均具有不错的诊断价值,但IFA+ FFA可及时发现合并的糖尿病虹膜病变,为及时治疗提供帮助.%AIM:To compare and analyze the diagnostic value of iris fluorescein angiography (IFA) combined with fundus fluorescein angiography (FFA),indocyanine green angiograph (ICGA),fundus fluorescein angiography in the diagnosis of early diabetic retinitis (DR).METHODS:Totally 70 patients (136 eyes) with early diabetic retinopathy enrolled in our hospital from August 2015 to August 2016 were selected in this study.All patients were respectively treated with ICGA,FFA and IFA+FFA,and the detection results of three kinds of imaging methods were analyzed.RESULTS:There were 120 pathological eyes (88.2％)were detected by FFA,124 pathological eyes (91.2％)were detected by ICGA,130 pathological eyes (95.6％)were detected by IFA+ FFA,and there was no significant difference in the detection rate between the three methods (P＞0.05).FFA detected 48 eyes with neovascularization,18 eyes with vitreous hemorrhage,38 eyes with macular edema,16 eyes without perfusion area;ICGA detected 49 eyes with neovascularization,38 eyes with macular edema,17 eyes with vitreous hemorrhage,20 eyes without perfusion area;IFA+ FFA detected 17 eyes with proliferative diabetic iridopathy (DI),22 eyes with non-proliferative DI,5 eyes with NVG,92 eyes without DI.CONCLUSION:In the diagnosis of early diabetic retinopathy,iris fluorescence angiography,fundus fluorescein angiography and indocyanine green angiography all have good diagnostic value,but IFA+FFA can detect the diabetic retinopathy in time and provide the help for the timely treatment.