飞秒激光LASIK术后角膜生物力学的改变

摘要

目的:探讨飞秒激光LASIK术后角膜生物力学指标的改变,为飞秒激光LASIK术的安全性研究提供理论依据.方法:选取2014-06/2016-06于我院行手术治疗的85例170眼近视患者,所有患者均采用飞秒激光LASIK术治疗,对符合纳入标准的病历资料进行回顾性分析.术前和术后3、6 mo采用眼反应分析仪测量角膜补偿眼压(corneal compensated intraocular pressure,IOPcc)、角膜阻力因子(corneal resistance factor,CRF)、角膜滞后量(corneal hysteresis,CH)以及模拟Goldmann眼压(Goldmann correlated IOP value,IOPg),采用A型超声测量仪测量中央角膜厚度.结果:术后3、6 mo中央角膜厚度显著低于术前,差异有统计学意义(P0.05);角膜切削厚度为98.67±7.56μm,CH和CRF变化量分别为3.40±0.34mmHg、3.55±0.43mmHg,角膜切削厚度与CH、CRF变化量呈明显正相关(r=0.232、0.254,P0. 05 ); the cornea cutting thickness was 98. 67 ± 7. 56μm, CH and CRF variation were 3. 40 ± 0. 34mmHg, 3. 55 ± 0. 43mmHg respectively, the cornea cutting thickness was positively correlated with CH, CRF variation ( r=0. 232, 0. 254; P<0. 001).? CONCLUSION: Femtosecond laser LASIK can apparently reduce corneal thickness as well as the corneal biomechanical indexes, the data at postoperative 3mo tends to be stable.