不同镇静方法在婴幼儿CTA检查中的应用研究

摘要

目的 观察不同镇静方法在先天性心脏病(CHD)婴幼儿CT血管成像(CTA)检查中的应用效果.方法 选取CTA检查的CHD婴幼儿158例,按CTA检查时间先后入组,分为A组和B组,各79例,A组患儿在检查前口服水合氯醛,B组患儿在检查前静脉推注丙泊酚法.观察2组给药前后心率、呼吸、血氧饱和度(SpO2),以及2组药物起效时间、术后苏醒时间、以及患儿的躁动发生率及Ramsay镇静评分.结果 给药前及给药后,2组患儿心率、呼吸、SpO2差异均无统计学意义(P>0.05).B组起效时间、苏醒时间均短于A组,躁动发生率低于A组,Ramsay镇静评分及CTA检查成功率高于A组,差异均有统计学意义(P<0.01).结论 静脉注射丙泊酚法在CHD婴幼儿CTA检查过程中有显著镇静效果,该方法安全、有效、起效和苏醒迅速,能够提高CTA检查效率.%Objective To observe the application of different methods of sedation for congenital heart disease (CHD) infants during computed tomography angiography (CTA) examination.Methods A total of 158 CHD infants undergoing CTA examination were randomly divided into two groups, with 79 cases in each group.Group A used oral chloral hydrate and group B used propofol intravenous injection method before CTA examination.The heart rate, breath rate, oxygen saturation (SpO2), onset time of drug, recovery time, emergence agitation and Ramsay sedation score were observed and compared between two groups.Results There was no significant difference in heart rate, breath rate and SpO2 between two groups (P>0.05).Compared with those in the Group A, infants in the group B had an earlier onset time of drug, earlier recovery time, lower incidence of emergence agitation, higher Ramsay sedation score and success rate of CTA examination, with significant difference (P<0.01).Conclusion Intravenous propofol method has obvious sedative effects for CHD infants during CTA examination, and it is safe, effective to improve the efficiency of CTA examination.