目的：探讨辅助生殖技术中中重度卵巢过度刺激综合征（OHSS ）的临床特征、高危因素、妊娠结局。方法回顾性分析我院生殖中心2010年4月至2014年4月间接受IVF／ICSI －ET 治疗的483个周期，选择发生中重度OHSS 的26个周期为OHSS 组，与随机筛选同期接受IVF／ICSI －ET 治疗时未发生OHSS的患者30个周期作为对照组，对比研究两者的相关指标。结果 OHSS 组年龄轻，多囊卵巢综合征（PCOS）患者比例大，注射HCG日E 2水平高，Gn总用量多，HCG日≥12 mm的卵泡数多，临床妊娠率高，两组比较有显著性差异（P＜0．05）。结论促排卵过程中应充分预测卵巢反应性，个体化选择促排卵方案，减少卵泡的募集，预防和降低中重度OHSS的发生率，提供IVF安全性。%Objective To explore the clinical characteristics ,risk factor ,pregnancy outcomes of moderate -severe ovarian hyperstimulation syndrome (OHSS) in assisted reproductive technique .Method From April 2 0 1 0 to April 2 0 1 4 ,4 8 3 cycles of IVF/ICSI-ET were analyzed retrospectively .2 6 cycles took place in the moderate-severe OHSS patients as OHSS groups ,3 0 cycles in non -OHSS as contol group by random .We compared pa-tient ,s characteristics and correlative parameters .Results The age ,the total doses of Gn ,the serum E2 levels on the day of hCG administration ,ulrasound monitoring follicle number greater than 1 2 mm in diameter on the day of hCG were significantly different between the OHSS group and the non -OHSS group(P<0 .05 ) .Con-clusion We should predict the ovarian reactivity fully ,choose ovulation induction programs individualized ,re-duce the raising of follicles to prevent the occurrence of OHSS .
展开▼
