Objective:To investigate the curative effect by MRI on therapy of Xikang injection on knee osteoarthritis. Methods:The data of knee osteoarthritis in 40 cases with clinically proved were collected. 40 cases with OA of the knee who used Xikang injection were evaluated by MRI, and the same cases were evaluated again after two courses,respectively. MRI showed hydrarthrus,marrow edema,changing of articular cartilage,synovium proliferatio and degeneration of meniscus. Results: 90% (36/40 ) hydrarthrus, marrow edema, articular cartilage damage were achieved control or turned better,and 10% (4/40) were progressive. The aging of menisci had no change after treatment. 42.5% (17/40) synovium proliferatiowere achieved control, and 50% (20/40), 7. 5% (3/40)were turned better and progressive. Conclusion; Hydrarthrus and marrow edema can be stimulated further absorption by Xikang injection,and the progress of articular cartilage damage, synovium proliferatio and degeneration of meniscusmay can be delayed. MRI to evaluate the efficacy of KOA is an ideal method.%目的:探讨膝康注射液治疗膝骨关节炎的磁共振(MRI)疗效.方法:符合纳入标准膝骨关节炎患者25人,病膝40例.关节腔内注射膝康注射液进行治疗,治疗前后进行MRI检查,对比分析关节腔积液、软骨下骨髓水肿、软骨破坏、滑膜增厚及半月板损伤的程度.结果:治疗后关节腔积液量、软骨下骨髓水肿范围明显好转,分别为80％ (32/40)、75％( 30/40)；关节软骨破坏得到控制67.5％ (27/40),好转22.5％ (9/40),仍有进展的为10％ (4/40)；半月板退行性改变程度在治疗前后无明显好转,但明显得到控制.滑膜增厚在治疗中得到控制占42.5％(17/40),进展和好转分别为7.5％ (3/40)、50％(20/40).结论:膝康注射液可促进膝关节腔积液、软骨下骨髓水肿的吸收,延缓软骨的破坏、滑膜的增厚及半月板的退变.MRI检查是评价膝骨性关节炎疗效的理想方法.
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