国内耐药肺炎链球菌的流行现状

摘要

Streptococcus pneumoniae is an important pathogen that causes devastating infectious diseases, such as bacterial rnpneumonia, otitis media and meningitis in both developed and developing countries. Due to the excessive use of antibiotics, the rernsistance of pneumococcal isolates to many of the commonly used antibiotics results in fewer effective antibiotics available for treatrnment. As the resistant S. pneumoniae is gradually approaching what the “superbug” is, the emergent situation demands our full atrntention and efforts in seeking short-and long-term solutions. This article provides an overview of the current status of drug resisrntance of S. pneumoniae and the related research in China.%肺炎链球菌可引起细菌性肺炎、中耳炎和脑膜炎等疾病,是当今发达国家和发展中国家共有的一个重要病原.由于抗生素长期的过度使用,许多肺炎链球菌菌株能够同时耐受多种常用的抗生素,使得临床可应用的有效抗生素越来越少.耐药肺炎链球菌正在朝着"超级细菌"方向发展.这种现状值得我们关注并寻求近期和长期的解决方法.本文对国内肺炎链球菌耐药现状及相关研究进行综述.