1例胃癌术后患者化学治疗所致恶心呕吐药学服务

摘要

Objective To provide reference for clinical pharmacist participating in management of nausea and vomiting induced by tumor chemotherapy. Methods The process of pharmaceutical care for a patient with severe vomiting caused by adjuvant chemotherapy after gastric cancer operation was described. Antiemetic application and drug adverse reactions were analyzed. A new treatment plan was given by clinical pharmacist. Results The suggestions were adopted by clinician. The vomiting was controlled and drug adverse reactions were dealt with. Conclusion To reduce the risk and improve the income of antiemetic,clinical pharmacists should pay more attention to clinical practice guideline,drug interaction and adverse reactions, provide the most suitable suggestions for clinicians according to pharmacology and evidence-based medicine.%目的：为临床药师参与化学治疗(化疗)所致恶心呕吐的管理提供参考。方法临床药师参与1例胃癌术后辅助化疗导致严重呕吐病例的监护过程。对化疗所致呕吐的预防和治疗药物应用、止吐药物不良反应识别和处理进行分析，并基于药理学与临床指南提出药物治疗建议。结果医师采纳药师建议，患者呕吐得到有效控制，止吐药物所致不良反应得到缓解。结论临床药师参与化疗所致恶心呕吐的管理，应注意对临床指南的理解和掌握，加强对止吐药物相互作用和不良反应的关注，并基于药理学和循证医学提供最佳的药物治疗建议，以保障患者用药的安全有效。