两种方法对幽门螺杆菌阳性溃疡的疗效观察

摘要

Objective: To observe different healing methods in treating helicobacter pylori positive ulcer. Method: 126 patients were selected in our hospital from March 2009 to May 2010 ,the patients were randomly divided into two groups: observing group ( amoxicillin, clarithromycin, omeprazole combination group)and control group (amoxicillin, metronidazole, ranitidine combination group ), each group with 63 cases, the treatment course was 8 weeks, and then compared the effect of two groups. Result: 41 cases were excellent,19 cases were markedly effective, the effective rate was 65.1％, the total effective rate was 95.2％ in observing group;28 cases in control group were excellent, 24 cases markedly effective, the effective rate was 44.4％, total effective rate was 82.5％. There were significant difference between the two groups (P＜0.01 ). The results were statistical significance. there were no obvious adverse reactions during the two groups.Conclusion: The healing effect of amoxicillin, clarithromycin, omeprazole triple therapy for helicobacter pylori-positive ulcers were ideal and worthy of clinical applying.%目的:观察不同治疗方法治疗幽门螺杆菌阳性溃疡的临床疗效,提高临床治疗水平.方法:选取我院自2009年3月至2010年5月收治的126例幽门螺杆菌阳性溃疡患者随机分为观察组(阿莫西林、克拉霉素、奥美拉唑联合用药组)和对照组(阿莫西林、甲硝唑、雷尼替丁联合用药组)各63例,治疗周期为8周,比较两组患者的治疗效果.结果:观察组显效41例,有效19例,显效率为65.1%,总有效率为95.2%;对照组显效28例,有效24例,显效44.4%,总有效率为82.5%.两组比较差异显著(P<0.01),具有统计学意义.两组患者在服用期间均未出现明显不良反应情况.结论:阿莫西林、克拉霉素、奥美拉唑三联疗法治疗幽门螺杆菌阳性溃疡效果理想,值得临床推广使用.