METHOD FOR ASSESSING THE SEVERITY OF GASTRIC ULCER WITH ULCER LOCALIZATION IN THE ANTRUM ASSOCIATED WITH HELICOBACTER PYLORI AND EPSTEIN-BARR VIRUS

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, in particular to gastroenterology. The substance of the invention lies in the fact that in patients with gastric ulcer with the localization of ulcers in the antrum of the stomach associated with Helicobacter pylori (H. pylori) and Epstein-Barr virus (EBV), not only H. pylori contamination of the gastric mucosa is assessed, but also using the polymerase chain reaction method, the number of EBV copies is detected per 105 cells of the infiltrate. When detecting the number of EBV copies from 10001 or more per 105 cells of the infiltrate, the severity of the course of the disease is assessed as severe. If the number of EBV copies is found from 1001 to 10,000 per 105 cells of the infiltrate, the severity of the course of the disease is assessed as average. If the number of EBV copies is found from 101 to 1000 per 105 cells of the infiltrate, the severity of the course of the disease is assessed as mild. If the number of EBV copies is detected up to 100 per 105 cells of the infiltrate, the treatment of the Epstein-Barr virus is carried out as if the severity of the disease was mild. Subject to the presentation of complaints and the detection of gastric ulcer or a picture of pronounced antral gastritis during fibrogastroduodenoscopy, in other cases, treatment of the Epstein-Barr virus is not required.;EFFECT: invention provides an increase in the efficiency of diagnostics of the course of gastric ulcer with ulcer localization in the antrum of the stomach associated with H. pylori and EBV, timely predicting the course of the disease and optimizing the treatment of patients, reducing the number of exacerbations.;1 cl, 1 tbl, 5 ex