64排螺旋CT评价冠状动脉及左心功能的临床价值

摘要

Objective: To assess the clinical value of 64-slice multidetector CT in evaluation of coronary artery disease and left ventricular function. Method: 322 patients with varying degrees of coronary artery stenosis were simultaneously performed coronary artery computed tomography angiography (CTA) and two-dimensional transthoracic echocardiography ( 2D-TTE ) examinations. Coronary artery degree of stenosis, extent and plaque features were assessed by using retrospective ECG gating technique. Meanwhile, left ventricular function data obtained from the two methods were compared. Result: 96.0％ (309/322 cases)were successfully evaluated by CTA. A total of 253 cases with coronary artery stenosis (40.51 ± 19.33％ )and 649 atherosclerotic plaques were detected. The left ventricular end-diastolic volume ( LV-EDV ) , left ventricular end-systolic volume ( LV-ESV), left ventricular ejection fraction ( LVEF), respectively obtained from 64-MDCT and 2D-TTE, There wasn't significant difference between the two methods. Conclusion: By a single CTA scan, the 64-MDCT, evaluating coronary artery disease and simultaneously measuring accurate indicators of left ventricular function, demonstrate a high clinical application value.%目的:研究64排螺旋CT同时评价冠状动脉及左心功能的临床应用价值.方法:322例同期行冠状动脉CTA(Computed Tomography Angiography)和二维经胸超声心动图(2-Dimensional TransThoracic Echocardiography,2D-TTE)检查,利用回顾性心电门控技术,评估冠状动脉狭窄程度、范围及斑块性质,同时获取左心功能数据与2D-TTE进行对比分析.结果:心脏CTA检查成功率为96.0%(309/322例),冠状动脉狭窄患者253例共649处硬化斑块,狭窄程度平均为40.51±19.33%;64-MDCT测得左心室舒张末期容积(left ventricular end-diastolic volume,LV-EDV)、左心室收缩末期容积(left ventricular end-systolic volume,LV-ESV)及左心室射血分数(left ventricular ejection fraction,LVEF)与2D-TTE检查结果间无显著性差异.结论:利用64-MDCT通过单次心脏CTA检查可以同时对冠状动脉情况及左心功能进行准确评价,有很高的临床应用价值.