复方α-酮酸片治疗慢性肾衰竭的疗效观察

摘要

目的:观察复方α-酮酸片治疗慢性肾衰竭的临床疗效.方法:54例患者随机分为对照组和实验组,对照组给予常规治疗,实验组在常规治疗基础上加用复方α-酮酸片,持续治疗8周,观察治疗前后两组生化指标的变化.结果:治疗后,实验组中TC、TG、SCr、BUN、血磷、PTH明显降低,ALB及血钙值明显提高,其差异具有统计学意义(P＜0.05)；与对照组比(较,各指标变化仍明显(P＜0.05).结论:复方α-酮酸片可有效保护肾功能,延缓肾脏衰竭进程.%Objective: To observe the effect of ketosteril in the treatment of chronic renal failure. Method ; 54 patients with chronic renal failure were randomly divided into 2 groups. The patients in control group were underwent conventional therapy, while patients in the experiment group were underwent ketosteril added by vein. Treatment courses lasted 8 weeks in both groups. Biochemical indicators were detected before and after therapy. Result: After the therapy, the values of BUN, Scr,TC,TG, phosphorus and PTH were reduced, while the ALB and hypocalceamia were promoted significantly in the experiment groups (P<0. 05 ). And there were significant difference between the values in experiment group and those in control group (P< 0.05). Conclusion: The ketosteril treatment for the chronic renal failure can protect the renal function and delay the process of renal failure.