封闭抗体与反复自然流产的相关性分析

摘要

目的:探讨封闭抗体与反复自然流产的关系.方法:对183例反复自然流产(病例组)和100例健康孕妇(对照组)的封闭抗体情况进行检查,并采用二变量的相关性检验,采用Spearman相关性分析进行统计学分析.结果:病例组BA阳性率为6.01%明显低于对照组BA阳性率15.00%,差异有明显的统计学意义(P<0.01),二变量的相关性检验采用Spearman相关性分析显示随着流产次数的增加BA阳性率明显下降,流产次数与BA阳性率呈现显著的负相关(r=-0.873,P<0.01).结论:封闭抗体与反复自然流产发病具有一定的相关性.%Objective: To investigate the relationship between blocking antibodies and recurrent spontaneous abortion. Method: Blocking antibodies was detected by enzyme-linked immunosorbent test (ELISA ) in 183 patients with primary recurrent spontaneous abortion, and 100 normal control, and bivariate correlations was used to analyze the relationship between blockingantibodies and recurrent spontaneous abortion. Result: The positive rate of case group was significantly lower than the control group, there was statistically significant difference ( P〈0. 01 ), Spearman correlation analysis showed the positive rate of BA showed a significant negative correlation ( r=-0. 873, P 〈 0. 01 ). Conclusion: Blocking antibodies is correlation with recurrent spontaneous abortion