目的：探讨超声实时组织弹性成像诊断慢性乙型肝炎肝纤维化的灵敏度及特异度，分析其临床应用价值。方法：选取在我院就诊并有肝穿刺病理学检查结果的慢性乙型肝炎患者60例。结果：60例患者肝纤维化病理分期S0期19例、S1期16例、S2期10例、S3期7例和S4期8例；超声实时组织弹性成像评分1分20例、2分16例、3分10例、4分7例及5分7例。病理结果显示肝纤维化41例、无肝纤维化19例；超声实时组织弹性成像评分判定肝纤维化40例、无肝纤维化20例。超声实时组织弹性成像灵敏度92．68％，特异度89．47％。结论：超声实时组织弹性成像评估慢性乙型肝炎肝纤维化具有较高的灵敏度与特异度，为肝纤维化的临床诊断提供了一种新的手段，并且具有无创，可反复检查，对观察患者病变进展具有重要的意义。%Objective:To investigate the sensitivity and specificity of ultrasound real-time tissue elas-tography in diagnosing hepatic fibrosis secondary to chronic hepatitis B and analyze the clinical application value .Method:60 patients with chronic hepatitis B examined by liver biopsy pathological examination in our hospital.Result:Among 60 patients, 19 were pathologically staged at So of hepatic fibrosis , 16 at S1 stage, 10 at S2 stage, 7 at S3 stage and 8 at S4;20 were scored 1 by ultrasound real-time tissue elastography , 16 cases scored 2, 10 cases scored 3, 7 cases scored 4 and 7 cases scored 5.As revealed by pathological re-sults, 41 cases had hepatic fibrosis and 19 cases had no hepatic fibrosis;as judged by ultrasound real-time tissue elastography score , 40 cases had hepatic fibrosis and 20 cases had no hepatic fibrosis .The sensitivity of ultrasound real-time tissue elastography was 92.68%and the specificity was 89.47%.Conclusion:Using ultrasound real-time tissue elastography to evaluate hepatic fibrosis secondary to chronic hepatitis B has com-paratively high sensitivity and specificity , which is a new method for clinical diagnosis of hepatic fibrosis , non-invasive and repeatable , and has an important significance for lesion development observation in the pa-tients.
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