改进宫腹腔镜诊治输卵管性不孕症的疗效评价及对应激因子与炎症因子的影响

摘要

目的:研究改进宫、腹腔镜诊治卵管性不孕症的疗效评价及对应激因子与炎症因子的影响.方法:选取2014年8月至2015年8月我院接诊的80例输卵管性不孕症患者作为本次研究对象.对照组采用传统宫、腹腔镜诊治,观察组采用改进宫、腹腔镜诊治,观察两组患者手术情况,治疗前后应激水平肾上腺素(E)、皮质醇(Cor)、促甲状腺激素(TSH),炎症因子白介素-2(IL-2)、白介素-6(IL-6)、白介素-8(IL-8)、C反应蛋白(CRP),治疗疗效.结果:观察组输卵管通畅率、宫内妊娠率大于对照组,再次异位妊娠率小于对照组[92.50%(37/40)vs75.00%(30/40)、95.00%(38/40)vs75.00%(30/40)、5.00%(2/40)vs22.50%(9/40)](P<0.05);观察组E、Cor小于对照组,TSH大于对照组[(96.16±10.25)ng/mL vs(152.17±16.03)ng/mL、(146.86±18.97)ng/mL vs(236.16±23.17)ng/mL、(3.10±0.50)mU/L vs(1.82±0.32)mU/L] (P<0.05);观察组IL-2、IL-6、IL-8、CRP小于对照组[(17.80±2.21)pg/mL vs(29.07±4.70)pg/mL、(43.21±5.86)pg/mL vs(54.26±6.23)pg/mL、(183.25±34.20)pg/mL vs(213.97±50.65)pg/mL、(5.03±0.81)pg/mL vs(6.12±0.90)pg/mL] (P<0.05);观察组总有效率优于对照组95.00%(38/40)vs75.00%(30/40)(P<0.05).结论:改进宫、腹腔镜诊治卵管性不孕症的疗效显著,可减少应激因子与炎症因子的表达,有利于患者的预后.%Objective:To study improved hysteroscopy combined with aparoscopy in treatment of tubal infertility stress factors and its effects on inflammatory factors.Methods: 80 patients of tubal infertility who received therapy from August 2014 to August 2015 in our hospital were selected as research objects.The control group was treated with tradition hysteroscopy combined with aparoscopy, while the observation group was treated with Improved hysteroscopy combined with aparoscopy, Then The stress level of adrenaline (E), cortisol(Cor), Thyroid stimulating hormone(TSH), inflammatory factors interleukin-2(IL-2), interleukin-6(IL-6), interleukin-8(IL-8), C reactive protein (CRP), treatment efficacy before and after treatment two groups of patients were compared.Results: After treatment, tubal patency rate, intrauterine pregnancy rate in observation group was than the control group, ectopic pregnancy rate in observation group was less than the control group[92.50%(37/40)vs75.00%(30/40),95.00%(38/40)vs75.00%(30/40),5.00%(2/40)vs22.50%(9/40)] (P<0.05);E,or in observation group was less than the control group, TSH in observation group was than the control group[(96.16±10.25)ng/ml vs(152.17±16.03)ng/ml、(146.86±18.97)ng/ml vs(236.16±23.17)ng/ml、(3.10±0.50)mU/L vs(1.82±0.32)mU/L] (P<0.05);IL-2、IL-6、IL-8、CRP in observation group was less than the control group[(17.80±2.21)pg/ml vs(29.07±4.70)pg/ml、(43.21±5.86)pg/ml vs(54.26±6.23)pg/ml、(183.25±34.20)pg/ml vs(213.97±50.65)pg/ml、(5.03±0.81)pg/ml vs(6.12±0.90)pg/ml] (P<0.05);The total effective rate of observation group was statistically higher than that in the control group95.00%(38/40)vs75.00%(30/40)(P<0.05).Conclusion:To improve the effect of hysteroscopy and laparoscopy in the diagnosis and treatment is well for tubal infertility, which can reduce the expression of stress factors and inflammatory factors, which is beneficial to the prognosis of the patients.