上海市北蔡镇老年女性骨质疏松症与生理因素关系分析

摘要

目的 了解上海市北蔡镇老年女性骨质疏松症(OP)与生理因素的关系,为本地区OP的防治提供参考.方法 使用美国GE公司的Lunar Prodigy Advance PA+ 300164型双能X线骨密度仪对398名上海市北蔡镇60～79岁老年女性正位腰椎和左股骨近端进行骨密度测定.结果 将老年女性以骨密度测定结果分为:OP组、骨量正常组及骨量减少组,3组对照初潮年龄差异无统计学意义(P＞0.05),闭经年龄、行经年限、行经天数、孕次差异有统计学意义(P＜0.05)；3组两两比较显示:骨量正常组与OP组比较在闭经年龄、行经年限、孕次方面差异有统计学意义(P＜0.05),在行经天数方面差异无统计学意义(P＞0.05)；骨量正常组与骨量减少组比较在闭经年龄、行经年限、行经天数方面差有统计学意义(P＜0.05)；骨量减少组与OP组比较在闭经年龄、行经天数、孕次方面差异有统计学意义(P＜0.05),在行经年限方面差异无统计学意义(P＞0.05).结论 上海市北蔡镇老年女性人群OP与女性生理因素密切相关,尤其闭经年龄早、行经年限短、行经天数少、孕次多的老年女性,应注意OP预防.%Objective To investigate the correlation between senile female osteoporosis (OP) and female physiological factors at Beicai Township of Shanghai. Methods The bone density was detected in lumbar spine and left proximal femur in 398 senile women ( age range;60 ~79 yr) by GE DEXA machine. Results According to the results of bone density detection, the senile women were divided into three groups: OP group, normal bone mass group and bone mass loss group. There was no significant difference in the menarche age among the three groups ( P > 0. 05 ) , however, there were significant differences in the amenorrhea age, menorrhea duration, menorrhea days and gravidity among the three groups ( P <0. 05) ,and there were significant differences in the amenorrhea age, menorrhea duration and gravidity between normal bone mass group and OP group ( P <0. 05) , however, there was no significant difference in the menorrhea days between the two groups ( P > 0. 05). There were significant differences in the amenorrhea age, menorrhea duration and menorrhea days between normal bone mass group and bone mass loss group ( P <0.05) ,and there were significant differences in the amenorrhea age, menorrhea days and gravidity between bone mass loss group and OP group ( P < 0. 05 ) , however, there was no significant difference in the menorrhea duration between the two groups ( P > 0. 05 ). Conclusion There is a close correlation between OP and female physiological factors at Beicai Township of Shanghai, especially, for the elderly women with earlier amenorrhea age, shorter menorrhea duration, less menorrhea days and more gravidity, who should pay much attention to the prevention and treatment of OP.