Objective To observe the effect of the method of regulating Qi for reducing turbid on functional dyspepsia with anxiety and depression. Methods 55 cases of unctional dyspepsia with anxiety and depression were randomly divided into two groups. Control group received western medicine. Treatment group received the method of regulating Qi for reducing turbid. The course was four weeks in two groups. Clinical curative effect was summarized after a course. Main symptoms score, HAMA score, HAMD score and 5 - HT levels were observed before and after treatment. Results The total effective rate in treatment group (93.55％) was higher than that in control group ( 83.33％, P ＜0.05 ). The symptoms score and 5 - HT levels after treatment were siguificantly improved in comparison with that before treatment in two groups ( P ＜ 0.05 ). Early satiety, belching and bloating score in treatment group were lower that those in control group after treatment ( P ＜ 0. 05 ). HAMA and HAMD score after treatment were significantly decreased in comparison with that before treatment in treatment groups ( P ＜ 0. 05 ). Conclusion The method of regulating Qi for reducing turbid can significantly improve the symptoms of FD with anxiety and depression, lower levels of 5 - HT, and has significant effect, no side effects.%目的 观察理气降浊方对功能性消化不良(FD)伴焦虑、抑郁患者的影响.方法 将55例FD伴焦虑、抑郁患者随机分为2组,对照组24例予西药治疗,治疗组31例予理气降浊方治疗.2组均4周为1个疗程,1个疗程后观察2组治疗前后主要症状计分、汉密尔顿焦虑量表(HAMA)评分、汉密尔顿抑郁量表(HAMD)评分及5-羟色胺(5-HT)水平变化情况.结果 治疗组总有效率93.55%,对照组总有效率83.33%,2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组.2组治疗后各症状计分及5-HT水平与本组治疗前比较均明显改善(P<0.05),且治疗组早饱、嗳气及腹胀计分与对照组治疗后比较明显下降(P<0.05).治疗组治疗后HAMA及HAMD评分与本组治疗前比较均明显下降(P<0.05).结论 理气降浊方可明显改善FD伴焦虑、抑郁患者症状,降低5-HT水平,疗效显著,无副作用.
展开▼
