医生治疗非小细胞肺癌的选择偏好研究

摘要

运用离散选择实验,分析医生对非小细胞肺癌不同治疗结局的权衡偏好,为促进医患共同参与医疗决策提供参考.结果显示,不同治疗结局属性影响医生处方偏好的权重和相对重要程度依次为:无进展生存期、重度不良反应发生风险、疾病控制率、轻度不良反应发生风险、给药方式.可见,疗效是医生治疗非小细胞肺癌最先考虑和最为看重的,其次是考虑控制药物毒性,给药方式对医生选择治疗方案的影响程度较低.%Discrete selection experiments were used to analyze the doctor's trade－off preference for different treatment outcomes of non－small cell lung cancer,and to provide reference for promoting the full participation of doctors and patients in medical decision－making.The results showed that the weight and relative importance of different treatment outcome attributes affecting doctors' prescription preferences were:progression－free survival,risk of severe adverse reactions,disease control rate,risk of mild adverse reactions,and method of drug administration. It can be seen that the curative effect is the first and most important consideration for doctors to treat non－small cell lung cancer. Secondly,it is also important to control the toxicity of the drug,and the method of drug administration has a lower influence on the doctor's choice of treatment plan.