目的 探讨颈内动脉内中膜厚度与短暂性脑缺血继发脑梗死的关系.方法 回顾分析资阳市第一人民医院神经内科收治的90例短暂性脑缺血发作(TIA)患者的临床资料.所有患者均行颈部超声检查,并随访一个月,了解其脑梗死发生情况.采用受试者工作特征曲线(ROC)分析颈内动脉内中膜厚度预测短暂性脑缺血发作继发脑梗死可能.结果 颈内动脉内中膜厚度为(0.96±0.18) mm,随访1个月后短暂性脑缺血患者继发脑梗死16例(发生率约17.8％),内中膜增厚组14例与未增厚组2例,脑梗死发生率不同(x2=4.514,P＜0.05)；颈内动脉内中膜厚度预测短暂性脑缺血发作继发脑梗死价值的ROC曲线下面积为0.73 (P＜0.05).结论 TIA患者颈内动脉粥样硬化发生率高,颈内动脉内中膜增厚患者继发脑梗死的风险增加.%Objective To investigate the correlation between carotid artery intima-media thickness and transient ischemic attack. Methods The clinical data of 90 patients with transient ischemic attack in the Frist People's Hospital of Ziyang City was retrospectively analyzed. All the patients underwent neck ultrasonography, and were followed up for one month in order to understand the incidence of cerebral infarction. Receiver operating characteristic curve (ROC curve) was applied to analyze the carotid artery intima-media thickness and predict the incidence of cerebral infarction secondary to TIA. Results The mean carotid artery intima-media thickness of all the patients was (0.96±0.18) mm. After followed up for one month, 16 patients had cerebral infarction (17.8%), including 14 in the intima-media thickening group and 2 in the intima-media non-thickening group, with statistically significant differences between the two groups (x2=4.514, P<0.05). The area under the curve of ROC which built by carotid artery intima-media thickness and cerebral infarction secondary to TIA is 0.73 (P<0.05). Conclusion Patients with transient ischemic attack have higher incidence of carotid atherosclerosis, and those with thickened carotid artery intima-media have a higher risk for cerebral infarction.
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