Objective To explore the value of multi-slice CT in the diagnosis of solitary fibrous tumor of the pleura (SFTP). Methods The clinical symptoms and CT imaging features of 8 patients clinically and pathologically diagnosed as SFTP were retrospectively analyzed, which were compared with histopathological results. Results All the lesions of the 8 patients were located in dirty pleura. CT-scan showed 6 cases of mass boundary finishing, 1 case of lobulated rim, 1 case of irregular shape, 5 cases of uniform density, and 3 cases with low density area in mass center. Six patients underwent contrast-enhanced CT, of which 4 showed non-uniform reinforcement and 2 showed uniform reinforcement, including 3 cases of tumors with enhancement of blood vessels. Pathological examination showed that the tumor was composed of spindle cells, with a number of arrangements:immunohistochemical Vimentin (+) in 7 cas-es, CD34 (+) in 8 cases, the bcl-2 positive (+) in 8 cases, Sl00 (-) in 7 cases. Conclusion SFTP patients have certain characteristic CT manifestations. CT examination has a certain value for SFTP positioning and the relationship be-tween tumor and surrounding tissue structure.%目的:探讨多层螺旋CT对胸部孤立性纤维瘤(SFTP)的诊断价值。方法回顾性分析经临床和肿瘤病理学确诊的8例SFTP患者的临床症状、螺旋CT影像特点,并与组织病理学结果进行对照。结果所有8例患者病变均位于脏层胸膜,CT平扫显示6例肿块边界光整,1例边缘呈分叶状,1例呈不规则形状;5例密度较均匀,3例肿块中心有低密度区。6例行对比增强后4例不均匀强化,2例强化均匀,其中3例肿块内出现增强的血管。病理学检查显示,肿瘤由梭形细胞构成,有多种排列方式;免疫组化Vimentin(+)7例、CD34(+)8例、bcl-2阳性(+)8例,Sl00(-)7例。结论 SFTP患者的CT表现具有一定的特征性,CT检查对SFTP的定位以及明确肿瘤与周围组织结构的关系有一定价值。
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