生化快速测定技术诊断需氧菌性阴道炎的临床价值

摘要

目的 探讨生化快速测定技术诊断需氧菌性阴道炎的临床价值.方法 以随机抽选的模式从2016年3月至2017年3月于南京市鼓楼区妇幼保健所进行需氧菌性阴道炎诊断的患者中抽选出86例患者,对其进行临床采样,分别进行生化快速测定技术检测和Donders湿片镜检法检测,比较两种检测方法的检测结果.结果 采用生化快速测定技术检测患者的阳性率为91.86%,阴性检测率为8.14%,与Donders湿片镜检法结果(阳性率87.20%,阴性率12.80%)比较差异无统计学意义(P>0.05);患者采用生化快速测定技术的敏感度为94.93%、阳性预测值为91.86%、阴性预测值为63.63%、特异度为63.63%;采用生化快速测定技术能快速检测pH值、唾液酸苷酶、白细胞脂酶、H2O2浓度、β-葡萄糖醛酸酶以及凝固酶等这些常用于判断患者确诊需氧菌性阴道炎的较好指标.结论 采用生化快速测定技术诊断需氧菌性阴道炎效果显著,具有较高的特异度以及敏感度,操作方法简单快捷.%Objective To study the clinical value of rapid biochemical assay in the diagnosis of aerobic vagini-tis.Methods Eighty-six patients suspected of aerobic vaginitis randomly selected from Maternal and Child Health In-stitute of Nanjing Gulou District from March 2016 to March 2017 were enrolled.Samples were collected and detected by rapid biochemical assay and Donders wet mount microscopy.The test results of the two detection methods were com-pared.Results The positive rate and negative rate were 91.86% and 8.14% for rapid biochemical assay,as compared with 87.20% and 12.80% for Donders wet mount microscopy(P>0.05).For rapid biochemical assay,the sensitivity,the positive predictive value, negative predictive value, specificity were 94.93%, 91.86%, 63.63%, 63.63%, respectively. Rapid biochemical assay can rapidly determine the common indexes used for diagnosis of aerobic vaginitis:pH value,si-alidase,leukocyte esterase,H2O2,beta-glucuronidase,and clotting enzyme.Conclusion Rapid biochemical assay in di-agnosis of aerobic vaginitis has high specificity and sensitivity,and simple operation.