红背山麻杆叶的化学成分研究（Ⅰ）--酚酸类及相关化合物

摘要

80% acetone extracts of the fresh leaves of Alchornea trewioides was successively separated by Sephadex LH-20,MCI gel CHP 20P,and Toyopearl Butyl-650C column chromatography to yield ten phenolic acids and related compounds.Their structures were elucidated by spectroscopic analyses as:salicylic acid(1),p-hydroxybenzoic acid (2),2,5-dihydroxybenzoic acid(3),3,4-dihydroxybenzoic acid(4),trans-p-coumaric acid(5),cis-p-coumaric acid(6), caffeic acid(7),caffeic acid methyl ester(8),gallic acid(9),and methyl gallate(10).Compounds 1-8,10 were isolated from the Alchornea for the first time.%采用80％丙酮提取石油醚萃取部位,利用凝胶、MCI 及 Toyopearl Butyl-650C 柱色谱进行分离纯化得到10个酚酸类及相关化合物。根据化合物的波谱数据分析鉴定为水杨酸(1)、对羟基苯甲酸(2)、2,5-二羟基苯甲酸(3)、3,4-二羟基苯甲酸(4)、反-对香豆酸(5)、顺-对香豆酸(6)、咖啡酸(7)、咖啡酸甲酯(8)、没食子酸(9)、没食子酸甲酯(10)。其中化合物1~8、10均为首次从本属植物中分离得到。