呼吸机辅助治疗急性有机磷农药中毒并呼吸衰竭的临床疗效

摘要

Objective The clinical efficacy of mechanical ventilation treatment of acute organophosphorus pesticide poisoning (AOPP) and respiratory failure. Methods We analyzed 112 cases admitted to our hospital from January 2009 to January 2012 AOPP and patients with respiratory failure were randomly divided into control group of 50 patients received conventional therapy. Observation group, 62 cases of ventilator-assisted therapy on the basis of routine treatment. Comparison of the two groups and their clinical treatment outcomes analyzed were compared between the two groups of awake time, atropine and pralidoxime chloride dose, duration of hospitalization and recovery rates. Results The patients in the waking hours, atropine and chlorine phosphorus given the amount of hospitalization time, recovery rates have a significant difference, statistically significant (P <0.05). Conclusion The acute organophosphorus pesticide poisoning (AOPP) and respiratory failure in patients with early mechanical ventilation for respiratory support for treatment, can significantly improve the success rate is worthy of clinical.%　　目的探讨呼吸机辅助治疗急性有机磷农药中毒(AOPP)并呼吸衰竭的临床疗效.方法分析我院自2009年1月至2012年1月收治的112例AOPP并呼吸衰竭患者，随机分为对照组50例，给予常规治疗.观察组62例，在常规治疗的基础上给予呼吸机辅助治疗.比较两组的对其临床治疗结果进行分析，比较两组的清醒时间、阿托品及氯磷定用药剂量、住院时间及治愈率.结果组患者在清醒时间、阿托品及氯磷定用量、住院时间、治愈率方面比较，均有显著性差异，在统计学上具有显著性意义(P<0.05).结论急性有机磷农药中毒(AOPP)并呼吸衰竭患者，早期应用机械通气呼吸支持进行救治，可显著提高抢救成功率，值得临床推广.