Objective To explore the value of high frequency ultrasonography in screening thyroid nodule in healthy physical examination. Methods The thyroid were examined among 12419 normal healthy subjects in inland and coastland of Zhejiang province by high frequency ultrasonography. Results The thyroid nodule detected rate in female individuals was 39.76%(2215/5571), while only 27.33%(1883/6848) of male were detected to have thyroid nodule, there was a difference between the genders (χ2=208.921,P<0.01). The rate of thyroid nodules gradually increased with age (χ2=278.403,P<0.01). The coastal area is significantly higher nodule incidence of inland area (χ2=306.55,P<0.01). The thyroid carcinoma detected rate was 0.4%. Inland and coastal regions the incidence ratio was 1∶1.156. Conclusion The prevalence of thyroid is relatively high in coastland of Zhejiang province receiving medical examination. Attention should be paid to the high iodine diet on thyroid effects.% 目的探讨高频超声在浙江省不同地区健康体检人群甲状腺结节的筛选价值.方法应用高频超声检查浙江省沿海及内陆地区12419例健康体检人群的甲状腺,比较沿海及内陆地区甲状腺结节的检出率.结果甲状腺结节女性的检出率为39.76%(2215/5571),男性的检出率为27.33%(1883/6848),女性明显高于男性(χ2=208.921,P<0.01).结节的检出率随着年龄增加逐渐上升(χ2=278.403,P<0.01)；沿海地区甲状腺结节检出率明显高于内陆地区(χ2=306.55,P<0.01),甲状腺癌检出率为0.4%,内陆、沿海发病率比为1∶1.156.结论浙江省沿海地区甲状腺结节的检出率较高,应重视高碘饮食对甲状腺的影响.
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