复治的脊柱结核外科治疗加短程化疗的临床研究

摘要

目的： 研究并探讨复治的脊柱结核外科治疗加短程化疗的临床效果。方法 研究选取在2009年6月至2012年12月收治的30例复治的脊柱结核患者，所有患者都自愿接受调查和服从所有准则，先进行外科手术治疗，清除病灶和融合植骨，根据药敏试验的结果以及抗结核的疗效制定相应的化疗方案，化疗期间观察放射影像、结核症状的变化和化验指标的变化。结果 患者化疗5周内以及术后的4个月内结核症状显著改善，CRP平均值和血沉明显下降，基本恢复正常；术后10个月内影像学检查没有内固定松动现象发生，外科治疗加短程化疗的有效率超过90%。结论 对复治的脊柱结核患者实施外科治疗加短程化疗对治疗效果有显著作用，病灶的清除能缩短化疗的时间，这对提高疗效有重要意义。%Objective To study and to explore the retreatment of the clinical effect of surgical treatment of spinal tuberculosis with dots. Methods Selection our hospital during June 2009 to December 2009 treated 30 cases of spinal tuberculosis in retreatment of patients, all of the patients are voluntary to answer surveys and obey all the rules, to surgical treatment, removal of lesion and bone graft fusion, according to the result of drug sensitive test and the curative effect of anti-tuberculosis chemotherapy regimens formulate corresponding, observed during chemotherapy radiation image changes, tuberculosis symptoms and laboratory indicators. Results Five weeks of chemotherapy and postoperative patients with TB symptoms improved signiifcantly within 4 months, the average CRP and blood sedimentation markedly reduced, basic returned to normal; Postoperative imaging examination in 10 months without internal ifxation loosening phenomenon occurs, surgery plus efifcient dots more than 90%. Conclusion Surgical treatment for recurrent patients with spinal tuberculosis with dots on treatment effects have signiifcant effect, the removal of the lesion can shorten the time of chemotherapy, which has important signiifcance to improve the curative effect.