Objective To evaluate the efficacy and safety of cefoperazone/sulbactam and levofloxacin in the treatment of community-acquired pneumonia(CAP). Methods 60 patients with CAP were randomly divided into two groups. Treatment group: the patients were treated with cefoperazone/sulbactam and levofloxacin. Control group: the patients were treated with cefoperazone/sulbactam alone. Both groups were treated for 10-14 days. To observe two groups of patients with clinical efficacy and adverse reaction. Results The total effective rate of treatment group was 96.75%, control group in the total efficiency was 84.56%, the results showed that there were significant differences between the two groups (P<0.05); the rates of the side effects were 10.79%and 8.36%. There were no significant differences between the two groups (P>0.05). Conclusion Cefoperazone/sulbactam and levofloxacin in the treatment of community-acquired pneumonia(CAP) can improve the curative effect, and well tolerated.% 目的观察头孢哌酮-舒巴坦联合左氧氟沙星治疗社区获得性肺炎(CAP)的临床疗效和不良反应。方法将60例 CAP 患者,随机分为两组,治疗组为头孢哌酮-舒巴坦联合左氧氟沙星组(n=30),对照组为单纯用头孢哌酮-舒巴坦(n=30,疗程均为10~14d,观察两组患者的临床疗效和不良反应。结果治疗组总有效率为96.75%,对照组的总有效率为84.56%,两组的临床疗效比较差异有统计学意义(P<0.05)。治疗组不良反应发生率10.79%,对照组不良反应发生率8.36%,两组不良反应发生率比较差异无统计学意义(P >0.05)。结论头孢哌酮-舒巴坦联合左氧氟沙星治 CAP 可提高疗效,且耐受性良好。
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