Objective To study and anaylze effect of intrauterine infection on neonatal blood glucose metabolic abnormalities. Methods Choosed 194 intrauterine infection neonate from Jan. 2009 to Dec. 2011 as study group, and choosed 162 healthy neonate as controlled group. Compared rate of blood glucose metabolic abnormalities in these two groups. Results Rate of blood glucose metabolic abnormalities in study group was higher than controlled group. Incidence of hyperglycemia in severe infection children was lower than mild infection (P <0.05). Conclusion Intrauterine infection of neonate could cause stress reaction on blood glucose metabolic abnormalities, we should strength blood sugar monitoring.% 目的研究分析宫内感染新生儿的血糖异常发生率以及其感染程度对血糖代谢的影响。方法回顾性分析2009年1月至2011年12月期间，我院收治的194例宫内感染患儿的临床资料，设为观察组；并选同期接受治疗的162例正常新生儿，设为对照组。观察组生儿出生后24h、72h 行血样检测，并对患儿的病情进展检测血电解质，行葡萄糖滴注治疗。比较两组血糖代谢异常的发生率。结果观察组中不同感染儿之间发生高血糖和低血糖的发生率不明显差异（P ＞0.05），但明显高于对照组，两组比较差异明显，具有统计学意义（P＜0.05）；重度感染患儿发生高血糖的发生率高于轻度感染组（P ＜0.05），血糖发生率不显著，但是重度感染组血糖降低值低于轻度感染组（P ＜0.05）。结论胎儿宫内感染会引起强烈的应激反应，致使内分泌紊乱的发生，引起血糖功能衰竭，对宫内感染的新生儿加强血糖监测十分必要。
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