Ⅰ类切口切缘拭子微生物培养对预防性使用抗生素的临床指导意义

摘要

Objective To check for pathogenic bacteria for type I incision, the results(with or without incision infection) of prophylactic use of antibiotics were analyzed to guide clinical antibiotic application.Methods The use of antibiotics 290 cases(control group) from January to December 2013 and 372 cases(experimental group) of non preventive use of antibiotics after the introduction of national policies from January to December 2014, a total of 662 patients(exception of patients with malignant tumor) with type I incision were collected about the culture and drug sensitivity test and medical records, then took comparative analysis.Results Two groups of 662 cases of patients with surgical incision were no infection, infection rate was 0, the results about growth of pathogenic bacteria of the cut edge were not found, the difference was not statistically significant between the two groups(P>0.05).Conclusion Not preventive use of antibiotics is safe in type I incision operation.%目的：对Ⅰ类手术切口（恶性肿瘤、糖尿病及有各种原因导致免疫低下的患者除外，下同）有无病原菌进行检查，同时对是否预防性使用抗生素的结果（有无切口感染）进行分析，以指导临床抗生素的应用。方法收集我院2013年1~12月常规使用抗生素预防切口感染290例（对照组）及2014年1~12月国家政策出台后未预防性使用抗生素的372例（实验组）Ⅰ类切口患者共662例，2组患者均于术中无菌留取切口切缘拭子标本行培养及药敏试验，收集患者病历资料，进行对比分析。结果两组662例患者手术切口均无感染，感染率为0，切口切缘拭子微生物培养结果均未发现有病原菌生长，两组之间差异无统计学意义（P＞0.05）。结论Ⅰ类切口手术中不预防性使用抗生素也是安全的。