Objective To investigate the effectiveness of fluoride varnish in preventing primary caries in 3-5 years old children in the kindergarten collective environment and provide necessary information for oral health care plans. Methods Children aged 3-5 years old were randomly assigned into two study groups. The test group was treated with fluoride var-nish and given oral hygiene instruction semi-annually for 4 times; the control group was only given oral hygiene instruction semi-annually. Follow-up examinations were conducted after 4 interventions to monitor primary caries increment among these children. Results After intervention, the caries prevalence of test group raised from 51. 61% to 59. 14%, with incidence of 7. 53% at last. In the control group, the prevalence before and after was 52. 61% and 73. 93%, with the in-cidence of 21. 33%. The differences of the prevalence, the dmft value and the incidence between the test group and con-trol group were significant. Conclusion Semi-annual application of fluoride varnish is effective in the prevention of dent-al caries in primary teeth of children and can improve the oral health of children.%目的：了解在幼儿园集体环境中,乳牙局部用氟预防龋齿的效果,为提高儿童防龋水平提供依据。方法将同一幼儿园410名3~5岁儿童纳入研究,按照单纯随机抽样原则分为试验组和对照组。试验组每半年进行1次多乐氟涂布,同时进行口腔健康教育,共干预4次；对照组儿童仅进行相同的口腔健康教育。分别在干预前和第4次干预后进行口腔检查,记录患龋状况,并进行统计学分析。结果试验组与对照组患龋率分别由干预前51.61%增至59.14%,52.61%增至73.93%；干预后龋齿发病率分别为7.53%及21.33%。干预后试验组患龋率、龋均、龋齿发病率均低于对照组,差异均有统计学意义(P<0.05)。结论在幼儿园使用多乐氟防龋,能有效降低乳牙龋的发病率,促进儿童的口腔健康。
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