Objective To investigate the effectiveness of fluoride varnish in preventing first permanent molars caries inschool-age children and provide necessary information for oral health instruction. Methods 378 children aged 6-7 years old in the first grade of primary school in dahua country, hechi city, Guangxi province (1053 first permanent mo-lars) were randomly recruited into 2 groups. The test group (542 first permanent molars in 191 children) was treated with fluoride varnish one time in a half year and given oral hygiene instruction 3 times;The control group (511 first permanent molars in 187 children) was only given oral hygiene instruction 3 times. All first permanent molars were checked after 18 months later for caries. Results After intervention, the caries prevalence rate in the test group raised from 21.99%to 27.75%compared with the control group from 24.60%to 37.43%. The caries incidence rate in test and control group was 5.76%and 12.83%respectively. There was a significant difference between 2 groups regardless of caries prevalence, car-ies incidence, the DMFT reduction, the DMFs reduction, the occlusal caries prevalence, the pit and fissure caries preva-lence, the proximal caries prevalence. Conclusion Semi-annual application of fluoride varnish is effective in the preven-tion of dental caries in first permanent molars , which was worth of being popularized in clinic.%目的 评价局部涂氟用于学龄儿童第一恒磨牙的防龋效果,为学龄儿童龋病防治提供参考依据.方法 选取广西河池市大化县某小学一年级6~7岁儿童378名(1053颗第一恒磨牙),按照随机抽样原则,分为试验组和对照组.试验组191名(542颗第一恒磨牙),对照组187名(511颗第一恒磨牙).试验组每半年涂布多乐氟1次,同时进行口腔健康教育,共计3次;对照组只进行相同的口腔健康教育.试验开始前检查两组儿童的第一恒磨牙龋患情况,试验18个月后复查.结果 试验组与对照组患龋率分别由干预前21.99%增至27.75%,24.60%增至37.43%;干预后发病率分别为5.76%及12.83%.干预后试验组患龋率、发病率、新增龋均、新增龋面均、 面患龋率、窝沟龋患龋率、邻面龋患龋率、牙面龋发病率均低于对照组,差异均有统计学意义(P<0.05).结论 局部涂氟能够有效预防第一恒磨牙龋的发生.
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